11 countries

Argentina, Brazil, Chile, Germany, Mexico, Poland, Portugal, Spain, United Kingdom, Uruguay and USA.

2 categories

For technology-based startups and scaleups with disruptive and innovative AI-powered solutions.

6 winners

In total, €120,000 will be distributed to 6 winners, access to Santander X 100 plus perks and benefits.

Banco Santander, Microsoft, and Oxentia Foundation join forces to bring you this global competition


This exciting initiative aims to support and promote the growth of the AI ecosystem, providing a platform for startups and scaleups to showcase their innovative AI solutions and connect with industry expertsinvestors, and world-class resources.


Our partnership with Microsoft and Oxentia Foundation will bring even more opportunities for the winning companies, including access to valuable resources and support to ensure the impact of AI on society is positive and beneficial.

The best startups and scaleups will receive cash prizes, access to Santander X 100, and the opportunity to pitch to Microsoft’s Venture Capital Fund (M12).

Additionally, the winning companies will travel to Silicon Valley for the Awards Ceremony on June 29, where they will get promotion and visibility, network with industry experts and investors.

Do not miss this chance to be part of the AI revolution and join us in shaping the future of technology. Apply today and be on your way to taking your AI solution to the next level!


Technology-based startups and scaleups from 11 countries, with disruptive and innovative AI-powered solutions.


Startups category

Legally incorporated in one of the participating countries, meeting at least one of the following criteria: annual income that does not exceed $300,000, with capital raised between $100,000 to $1 million, or between 2 and 25 fulltime employees.


Scaleups category

Legally incorporated for at least two years in one of the participating countries, meeting at least one of the following criteria: annual income over $300,000, more than $1 million capital raised, or over 25 fulltime employees.

Honorable mention

Awards Ceremony

On June 29th, the six winners of the Santander X Global Challenge | The AI Revolution were announced. This global challenge was driven in collaboration with Microsoft and the Oxentia Foundation, and more than 540 startups and scaleups from 11 countries participated. 

After the ceremony, which took place at Microsoft's campus in Silicon Valley (USA), the winners will receive a total of 120,000 euros in prizes and access to #SantanderX100. Additionally, they will have the opportunity to present their projects to M12, Microsoft's Venture Capital, and access to #OpenAI APIs upon the company's approval.

Perks & Benefits

The winning teams will receive a host of benefits to help them continue developing their solutions. These benefits include a cash prize, mentoring by Microsoft AI experts, as well as membership to Santander X 100, the prime community of Santander X's most promising ventures, and they will travel to Silicon Valley for the Awards Ceremony.


Additionally, the winning teams will receive recognition and promotion through Microsoft and Santander's media channels.

Silicon Valley

Silicon Valley

Invitation to one team member per winning team to the Awards Ceremony at Silicon Valley. The invitation includes travel, accommodation and local transportation expenses.

Santander X 100

Santander X 100

Access to Santander X 100, the prime community of Santander X's most exceptional entrepreneurial startups and scaleups.



Cash prize

Cash prize

€ 120.000 for 6 winners:


3 startups: €10,000 each


3 scaleups: €30,000 each



Promotion on Banco Santander's social media and official channels.



Coaching from Microsoft's Co-Innovation VP and Microsoft for Startups Executives.







Access to OpenAI APIs subject to approval from Microsoft.




Pitch to Microsoft VC

The opportunity to pitch to Microsoft's Venture Capital (M12).





Key dates


Applications are open for AI-powered startups and scaleups in Santander X.

Finalists announcement

The 20 finalists announcement, 10 startups and 10 scaleups.


Pitch day

The 20 finalists are supported by international mentors to prepare a pitch to the jury.

Awards ceremony

The 6 winners travel to Silicon Valley to be recognized.


Our commitment


Banco Santander

Banco Santander maintains a firm commitment to progress and inclusive and sustainable growth with a pioneering and consolidated commitment to education, employability and entrepreneurship, which it has been developing for more than 26 years and distinguishes it from other financial institutions in the world.

The bank has allocated more than 2,200 million euros and has supported more than 1 million people and companies through agreements with more than 1,300 universities.



Microsoft (Nasdaq “MSFT” @microsoft) enables digital transformation for the era of an intelligent cloud and an intelligent edge. Its mission is to empower every person and every organization on the planet to achieve more.

Microsoft is committed to serve as a trusted partner, enabling local startups to bring their ideas into fruition on the global stage and empowering them with access to technology tools.


Oxentia Foundation

Oxentia grew out of Oxford University's technology transfer company, Oxford University Innovation, with the aim of providing specialised innovation management services to public and private sector customers throughout the world.

Oxentia's approach builds on Oxford's strong tradition of globally supporting early-stage innovators and entrepreneurs to promote innovative projects that impact the UN’s Sustainable Development Goals.

The Oxentia Foundation was created to support Oxentia's goal of addressing global inequalities through innovation and entrepreneurship activities.